Smart NanoCare addresses a fundamental challenge in next-generation digital healthcare: enabling reliable, energy-efficient communication among nanoscale devices operating inside the human body. Conventional electromagnetic communication is poorly suited to in-vivo environments due to severe attenuation and biological constraints. This project proposes a novel molecular communication framework for the Internet of Nano-Things (IoNT), specifically tailored for confined biological spaces such as blood vessels and cellular environments.

The core contribution of Smart NanoCare is the development of accurate point-to-point molecular communication models that account for non-ideal biological boundaries, heterogeneous receptor distributions, and anomalous diffusion processes. By moving beyond idealized free-space assumptions, the project introduces realistic channel models that better reflect physiological conditions. Building on these models, the project develops innovative interference mitigation techniques that exploit boundary absorption and reflection properties to control inter-symbol interference, transforming a major limitation of molecular communication into a performance advantage.

Energy efficiency is a central design objective. Smart NanoCare introduces optimized molecule-release strategies and boundary-aware signalling schemes that significantly reduce energy consumption in nanoscale devices, thereby extending their operational lifetime. A key innovation of the project is the integration of digital twin technology: virtual replicas of molecular nanonetworks that run in parallel with physical systems. These digital twins enable real-time simulation, monitoring, and predictive optimization of in-vivo communication channels, providing a powerful tool for system design and performance evaluation.

The project will deliver validated analytical models, simulation frameworks, energy-efficient communication protocols, and a functional digital twin platform, supported by high-impact journal and conference publications. By enabling reliable intra-body nano-communication, Smart NanoCare lays the foundation for transformative medical IoT applications, including real-time health monitoring, targeted drug delivery, and personalized therapies. Aligned with Dubai’s Research, Development, and Innovation priorities, the project advances frontier technologies in digital health and positions molecular communication and digital twins as key enablers of future smart healthcare ecosystems.