DUBAI-BioCHIP: Development of a Bioprinted and AI-Integrated Individualized Organoid-on-CHIP Platform for Patient-Specific Medicine

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Mohamed Ahmed Jamal

Hamdan Bin Mohammed College of Dental Medicine Mohammed Bin Rashid University of Medicine and Health Sciences.

"Dubai-BioCHIP is a project driven by my passion for stem cell biology, organoid engineering, and translational research. It aims to create patient-specific models that can transform how we study disease, test therapies, and personalize treatment. This initiative represents not only a scientific milestone but also a bold step toward positioning Dubai as a global hub for next-generation biomedical innovation.”

Dubai-BioCHIP aims to establish a transformative Organoid-on-Chip (OrgOC) platform replicating patient-specific biology for precision medicine. By combining hiPSC technology, neural crest and endothelial progenitors, 3D bioprinting, and Artificial Intelligence (AI), the project will create highly personalized organoid models that simulate disease and treatment response. Dual bioprinting technologies, extrusion for tissues and DLP for chip fabrication, enable scalable, in-house biofabrication. AI will support optimization, quality control, and predictive analysis throughout the pipeline. A cryopreservation biobanking protocol ensures reproducibility and reusability. This platform not only offers an ethical and efficient alternative to clinical trials but is designed for eventual commercialization. Dubai-BioCHIP goes beyond research by establishing a sustainable innovation ecosystem that elevates Dubai’s standing in global biomedical science. It empowers local talent, creates IP pathways, and positions Dubai to lead in next-generation healthcare technologies, fulfilling key translational, educational, and national strategic goals in life sciences innovation.